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TitleIdentification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
Journal, issue, pagesChemmedchem, Vol. 11, Page 893-899, Year 2016
Publish dateOct 12, 2015 (structure data deposition date)
AuthorsPatrone, J.D. / Pelz, N.F. / Bates, B.S. / Souza-Fagundes, E.M. / Vangamudi, B. / Camper, D.V. / Kuznetsov, A.G. / Browning, C.F. / Feldkamp, M.D. / Frank, A.O. ...Patrone, J.D. / Pelz, N.F. / Bates, B.S. / Souza-Fagundes, E.M. / Vangamudi, B. / Camper, D.V. / Kuznetsov, A.G. / Browning, C.F. / Feldkamp, M.D. / Frank, A.O. / Gilston, B.A. / Olejniczak, E.T. / Rossanese, O.W. / Waterson, A.G. / Chazin, W.J. / Fesik, S.W.
External linksChemmedchem / PubMed:26748787
MethodsX-ray diffraction
Resolution1.21 Å
Structure data

PDB-5e7n:
Crystal Structure of RPA70N in complex with VU0085636
Method: X-RAY DIFFRACTION / Resolution: 1.21 Å

Chemicals

ChemComp-5KR:
2-({3-[(4-bromophenyl)sulfamoyl]-4-methylbenzoyl}amino)benzoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING/INHIBITOR / Inhibitor / Complex / PROTEIN BINDING-INHIBITOR complex

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