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-Structure paper
Title | Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations. |
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Journal, issue, pages | J. Med. Chem., Vol. 59, Page 592-608, Year 2016 |
Publish date | Sep 3, 2015 (structure data deposition date) |
Authors | Cavalier, M.C. / Ansari, M.I. / Pierce, A.D. / Wilder, P.T. / McKnight, L.E. / Raman, E.P. / Neau, D.B. / Bezawada, P. / Alasady, M.J. / Charpentier, T.H. ...Cavalier, M.C. / Ansari, M.I. / Pierce, A.D. / Wilder, P.T. / McKnight, L.E. / Raman, E.P. / Neau, D.B. / Bezawada, P. / Alasady, M.J. / Charpentier, T.H. / Varney, K.M. / Toth, E.A. / MacKerell, A.D. / Coop, A. / Weber, D.J. |
External links | J. Med. Chem. / PubMed:26727270 |
Methods | X-ray diffraction |
Resolution | 1.528 - 1.742 Å |
Structure data | PDB-5dkn: PDB-5dkq: PDB-5dkr: |
Chemicals | ChemComp-CA: ChemComp-B7I: ChemComp-HOH: ChemComp-5D0: ChemComp-5CZ: |
Source |
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Keywords | METAL BINDING PROTEIN/INHIBITOR / malignant melanoma / calcium binding / covalent inhibitor / METAL BINDING PROTEIN-INHIBITOR complex / complex |