+Search query
-Structure paper
Title | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. |
---|---|
Journal, issue, pages | Sci Rep, Vol. 6, Page 25559-25559, Year 2016 |
Publish date | Jul 8, 2015 (structure data deposition date) |
Authors | Camilloni, C. / Sala, B.M. / Sormanni, P. / Porcari, R. / Corazza, A. / De Rosa, M. / Zanini, S. / Barbiroli, A. / Esposito, G. / Bolognesi, M. ...Camilloni, C. / Sala, B.M. / Sormanni, P. / Porcari, R. / Corazza, A. / De Rosa, M. / Zanini, S. / Barbiroli, A. / Esposito, G. / Bolognesi, M. / Bellotti, V. / Vendruscolo, M. / Ricagno, S. |
External links | Sci Rep / PubMed:27150430 |
Methods | X-ray diffraction |
Resolution | 1.49 - 1.75 Å |
Structure data | PDB-5cfh: PDB-5cka: PDB-5ckg: |
Chemicals | ChemComp-HOH: ChemComp-GOL: ChemComp-ACT: ChemComp-PEG: |
Source |
|
Keywords | IMMUNE SYSTEM / Aggregation propensity / Amyloid / beta-sandwitch / fold stability |