+Search query
-Structure paper
Title | A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. |
---|---|
Journal, issue, pages | Science, Vol. 349, Page 1301-1306, Year 2015 |
Publish date | Jul 14, 2015 (structure data deposition date) |
Authors | Impagliazzo, A. / Milder, F. / Kuipers, H. / Wagner, M.V. / Zhu, X. / Hoffman, R.M. / van Meersbergen, R. / Huizingh, J. / Wanningen, P. / Verspuij, J. ...Impagliazzo, A. / Milder, F. / Kuipers, H. / Wagner, M.V. / Zhu, X. / Hoffman, R.M. / van Meersbergen, R. / Huizingh, J. / Wanningen, P. / Verspuij, J. / de Man, M. / Ding, Z. / Apetri, A. / Kukrer, B. / Sneekes-Vriese, E. / Tomkiewicz, D. / Laursen, N.S. / Lee, P.S. / Zakrzewska, A. / Dekking, L. / Tolboom, J. / Tettero, L. / van Meerten, S. / Yu, W. / Koudstaal, W. / Goudsmit, J. / Ward, A.B. / Meijberg, W. / Wilson, I.A. / Radosevic, K. |
External links | Science / PubMed:26303961 |
Methods | X-ray diffraction |
Resolution | 3.6 - 4.3 Å |
Structure data | PDB-5cjq: PDB-5cjs: |
Chemicals | ChemComp-NAG: |
Source |
|
Keywords | VIRAL PROTEIN/IMMUNE SYSTEM / hemagglutinin / trimer / influenza / immunogen / monoclonal / antibody / neutralizing / influenza vaccine / glycoprotein / VIRAL PROTEIN-IMMUNE SYSTEM complex |