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-Structure paper
Title | Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 137, Page 9459-9468, Year 2015 |
Publish date | Jul 1, 2015 (structure data deposition date) |
![]() | Oyen, D. / Fenwick, R.B. / Stanfield, R.L. / Dyson, H.J. / Wright, P.E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.199 - 1.5 Å |
Structure data | ![]() PDB-5cc9: ![]() PDB-5ccc: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-DDF: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / Folate metabolism |