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Structure paper

TitleSelective small-molecule inhibition of an RNA structural element.
Journal, issue, pagesNature, Vol. 526, Page 672-677, Year 2015
Publish dateJun 17, 2015 (structure data deposition date)
AuthorsHowe, J.A. / Wang, H. / Fischmann, T.O. / Balibar, C.J. / Xiao, L. / Galgoci, A.M. / Malinverni, J.C. / Mayhood, T. / Villafania, A. / Nahvi, A. ...Howe, J.A. / Wang, H. / Fischmann, T.O. / Balibar, C.J. / Xiao, L. / Galgoci, A.M. / Malinverni, J.C. / Mayhood, T. / Villafania, A. / Nahvi, A. / Murgolo, N. / Barbieri, C.M. / Mann, P.A. / Carr, D. / Xia, E. / Zuck, P. / Riley, D. / Painter, R.E. / Walker, S.S. / Sherborne, B. / de Jesus, R. / Pan, W. / Plotkin, M.A. / Wu, J. / Rindgen, D. / Cummings, J. / Garlisi, C.G. / Zhang, R. / Sheth, P.R. / Gill, C.J. / Tang, H. / Roemer, T.
External linksNature / PubMed:26416753
MethodsX-ray diffraction
Resolution2.93 Å
Structure data

PDB-5c45:
Selective Small Molecule Inhibition of the FMN Riboswitch
Method: X-RAY DIFFRACTION / Resolution: 2.93 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-51B:
(6M)-2-[(3S)-1-{[2-(methylamino)pyrimidin-5-yl]methyl}piperidin-3-yl]-6-(thiophen-2-yl)pyrimidin-4-ol

Source
  • fusobacterium nucleatum (bacteria)
KeywordsRNA/INHIBITOR / RNA / TRANSLATION / RNA-INHIBITOR complex

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