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Structure paper

TitleBTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression
Journal, issue, pagesChem. Biol., Vol. 17, Page 1282-1294, Year 2010
Publish dateApr 7, 2016 (structure data deposition date)
AuthorsKimura, H. / Sato, Y. / Tajima, Y. / Suzuki, H. / Yukitake, H. / Imaeda, T. / Kajino, M. / Oki, H. / Takizawa, M. / Tanida, S.
External linksChem. Biol. / PubMed:21168764
MethodsX-ray diffraction
Resolution1.37 Å
Structure data

PDB-5b4o:
Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14
Method: X-RAY DIFFRACTION / Resolution: 1.37 Å

Chemicals

ChemComp-6DQ:
2-pyridin-3-yl-1,3-benzothiazin-4-one

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE

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