+Search query
-Structure paper
Title | Clinical Candidate Vt-1161'S Antiparasitic Effect in Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme Cyp51 from Trypanosoma Cruzi. |
---|---|
Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 60, Page 1058-, Year 2015 |
Publish date | Feb 26, 2015 (structure data deposition date) |
![]() | Hoekstra, W.J. / Hargrove, T.Y. / Wawrzak, Z. / Da Gama Jaen Batista, D. / Da Silva, C.F. / Nefertiti, A.S.G. / Rachakonda, G. / Schotzinger, R.J. / Villalta, F. / Soeiro, M.D.N.C. / Lepesheva, G.I. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.75 Å |
Structure data | ![]() PDB-5ajr: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-VT1: |
Source |
|
![]() | OXIDOREDUCTASE / CYTOCHROME P450 / CYP51 / MONOOXYGENASE / STEROL BIOSYNTHESIS / EUKARYOTIC MEMBRANES / CYTOCHROME P450 FOLD / ENDOPLASMIC RETICULUM MEMBRANE |