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TitleSynthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin.
Journal, issue, pagesBioorg. Med. Chem., Vol. 23, Page 2819-, Year 2015
Publish dateJan 9, 2015 (structure data deposition date)
AuthorsKnobloch, G. / Jabari, N. / Stadlbauer, S. / Schindelin, H. / Kohn, M. / Gohla, A.
External linksBioorg. Med. Chem. / PubMed:25783190
MethodsX-ray diffraction
Resolution2.751 Å
Structure data

PDB-5aes:
Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.751 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-5B0:
{2-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]ethyl}phosphonic acid

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / PDXP / PLPP / HALOACID DEHALOGENASE / HAD PHOSPHATASE / HAD HYDROLASE

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