Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase Gamma for the Treatment of Respiratory Disease.
Journal, issue, pages	J. Med. Chem., Vol. 58, Page 7381-, Year 2015
Publish date	Aug 26, 2015 (structure data deposition date)
Authors	Down, K. / Amour, A. / Baldwin, I.R. / Cooper, A.W.J. / Deakin, A.M. / Felton, L.M. / Guntrip, S.B. / Hardy, C. / Harrison, Z.A. / Jones, K.L. ...Down, K. / Amour, A. / Baldwin, I.R. / Cooper, A.W.J. / Deakin, A.M. / Felton, L.M. / Guntrip, S.B. / Hardy, C. / Harrison, Z.A. / Jones, K.L. / Jones, P. / Keeling, S.E. / Le, J. / Livia, S. / Lucas, F. / Lunniss, C.J. / Parr, N.J. / Robinson, E. / Rowland, P. / Smith, S. / Thomas, D.A. / Vitulli, G. / Washio, Y. / Hamblin, J.N.
External links	J. Med. Chem. / PubMed:26301626
Methods	X-ray diffraction
Resolution	2.42 - 2.44 Å
Structure data	PDB-5ae8: Crystal structure of mouse PI3 kinase delta in complex with GSK2269557 Method: X-RAY DIFFRACTION / Resolution: 2.42 Å PDB-5ae9: Crystal structure of mouse PI3 kinase delta in complex with GSK2292767 Method: X-RAY DIFFRACTION / Resolution: 2.44 Å
Chemicals	ChemComp-VVX: 6-(1H-Indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole ChemComp-HOH: WATER ChemComp-OKO: N-[5-[4-(5-{[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]METHYL}-1,3-OXAZOL-2-YL)-1H-INDAZOL-6-YL]-2-(METHYLOXY)-3-PYRIDINYL]METHANESULFONAMIDE
Source	mus musculus (house mouse)
Keywords	TRANSFERASE / PI3 KINASE DELTA