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Structure paper

TitleStructural integration in hypoxia-inducible factors.
Journal, issue, pagesNature, Vol. 524, Page 303-308, Year 2015
Publish dateMay 7, 2015 (structure data deposition date)
AuthorsWu, D. / Potluri, N. / Lu, J. / Kim, Y. / Rastinejad, F.
External linksNature / PubMed:26245371
MethodsX-ray diffraction
Resolution2.355 - 3.902 Å
Structure data

PDB-4zp4:
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex
Method: X-RAY DIFFRACTION / Resolution: 2.355 Å

PDB-4zph:
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-4zpk:
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-4zpr:
Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA
Method: X-RAY DIFFRACTION / Resolution: 3.902 Å

PDB-4zqd:
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3
Method: X-RAY DIFFRACTION / Resolution: 2.87 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PRL:
PROFLAVIN

ChemComp-0X3:
N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine

Source
  • mus musculus (house mouse)
KeywordsPROTEIN TRANSPORT/TRANSCRIPTION / ARNT / HIF-2a complex / bHLH-PAS / PROTEIN TRANSPORT-TRANSCRIPTION complex / HIF-2a / Proflavine / PROTEIN TRANSPORT/TRANSCRIPTION/DNA / HRE / PROTEIN TRANSPORT-TRANSCRIPTION-DNA complex / HIF-1a / 0X3

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