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-Structure paper
Title | Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 7370-7380, Year 2015 |
Publish date | Apr 23, 2015 (structure data deposition date) |
Authors | Lau, J. / Bloch, P. / Schaffer, L. / Pettersson, I. / Spetzler, J. / Kofoed, J. / Madsen, K. / Knudsen, L.B. / McGuire, J. / Steensgaard, D.B. ...Lau, J. / Bloch, P. / Schaffer, L. / Pettersson, I. / Spetzler, J. / Kofoed, J. / Madsen, K. / Knudsen, L.B. / McGuire, J. / Steensgaard, D.B. / Strauss, H.M. / Gram, D.X. / Knudsen, S.M. / Nielsen, F.S. / Thygesen, P. / Reedtz-Runge, S. / Kruse, T. |
External links | J. Med. Chem. / PubMed:26308095 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-4zgm: |
Chemicals | ChemComp-32M: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN / GLP-1 / receptor / complex |