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-Structure paper
Title | Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. |
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Journal, issue, pages | Mol. Pharmacol., Vol. 88, Page 982-992, Year 2015 |
Publish date | Apr 22, 2015 (structure data deposition date) |
![]() | Stein, A.J. / Bain, G. / Prodanovich, P. / Santini, A.M. / Darlington, J. / Stelzer, N.M. / Sidhu, R.S. / Schaub, J. / Goulet, L. / Lonergan, D. ...Stein, A.J. / Bain, G. / Prodanovich, P. / Santini, A.M. / Darlington, J. / Stelzer, N.M. / Sidhu, R.S. / Schaub, J. / Goulet, L. / Lonergan, D. / Calderon, I. / Evans, J.F. / Hutchinson, J.H. |
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Methods | X-ray diffraction |
Resolution | 1.75 - 2.95 Å |
Structure data | ![]() PDB-4zg6: ![]() PDB-4zg7: ![]() PDB-4zg9: ![]() PDB-4zga: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-4NY: ![]() ChemComp-SCN: ![]() ChemComp-HOH: ![]() ChemComp-4O0: ![]() ChemComp-NKN: ![]() ChemComp-CL: ![]() ChemComp-4O2: ![]() ChemComp-EDO: ![]() ChemComp-ACD: ![]() ChemComp-4O3: |
Source |
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![]() | Hydrolase/Hydrolase Inhibitor / Autotaxin / ENPP2 / inhibitor / Hydrolase-Hydrolase Inhibitor complex |