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-Structure paper
Title | Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration. |
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Journal, issue, pages | J. Biol. Chem., Vol. 290, Page 21773-21786, Year 2015 |
Publish date | Apr 21, 2015 (structure data deposition date) |
![]() | Koenig, P. / Lee, C.V. / Sanowar, S. / Wu, P. / Stinson, J. / Harris, S.F. / Fuh, G. |
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Methods | X-ray diffraction |
Resolution | 2.27 - 2.75 Å |
Structure data | ![]() PDB-4zff: ![]() PDB-4zfg: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-CA: |
Source |
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![]() | SIGNALING PROTEIN/IMMUNE SYSTEM / Fab / DAF / angiogenesis / Tie receptor / SIGNALING PROTEIN-IMMUNE SYSTEM complex |