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Structure paper

TitleInsights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.
Journal, issue, pagesBiochem. J., Vol. 475, Page 571-585, Year 2018
Publish dateApr 4, 2015 (structure data deposition date)
AuthorsKoag, M.C. / Lee, S.
External linksBiochem. J. / PubMed:29301983
MethodsX-ray diffraction
Resolution2.444 - 2.752 Å
Structure data

PDB-4z6c:
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable CTP
Method: X-RAY DIFFRACTION / Resolution: 2.677 Å

PDB-4z6d:
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-4z6e:
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE
Method: X-RAY DIFFRACTION / Resolution: 2.752 Å

PDB-4z6f:
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE
Method: X-RAY DIFFRACTION / Resolution: 2.444 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-0KX:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine

ChemComp-HOH:
WATER

ChemComp-1FZ:
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / DNA polymerase / TRANSFERASE-DNA complex

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