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-Structure paper
Title | A Minimal beta-Lactone Fragment for Selective beta 5c or beta 5i Proteasome Inhibitors. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 54, Page 7810-7814, Year 2015 |
Publish date | Mar 27, 2015 (structure data deposition date) |
Authors | Groll, M. / Korotkov, V.S. / Huber, E.M. / de Meijere, A. / Ludwig, A. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:25973989 |
Methods | X-ray diffraction |
Resolution | 3 Å |
Structure data | PDB-4z1l: |
Chemicals | ChemComp-MG: ChemComp-CL: ChemComp-4KF: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE / Proteasome / Inhibitor / Binding Analysis / Lead Structure Motif / HYDROLASE-HYDROLASE INHIBITOR complex |