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-Structure paper
Title | Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 137, Page 4358-4367, Year 2015 |
Publish date | Mar 27, 2015 (structure data deposition date) |
Authors | Lee, C. / Park, H.K. / Jeong, H. / Lim, J. / Lee, A.J. / Cheon, K.Y. / Kim, C.S. / Thomas, A.P. / Bae, B. / Kim, N.D. ...Lee, C. / Park, H.K. / Jeong, H. / Lim, J. / Lee, A.J. / Cheon, K.Y. / Kim, C.S. / Thomas, A.P. / Bae, B. / Kim, N.D. / Kim, S.H. / Suh, P.G. / Ryu, J.H. / Kang, B.H. |
External links | J. Am. Chem. Soc. / PubMed:25785725 |
Methods | X-ray diffraction |
Resolution | 2.703 - 3.3 Å |
Structure data | PDB-4z1f: PDB-4z1g: PDB-4z1h: PDB-4z1i: |
Chemicals | ChemComp-H71: ChemComp-HOH: ChemComp-94M: ChemComp-4KP: ChemComp-ANP: ChemComp-MG: |
Source |
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Keywords | CHAPERONE / Mitochondrial Hsp90 / AMPPNP |