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| Title | A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX. |
|---|---|
| Journal, issue, pages | Acta Crystallogr F Struct Biol Commun, Vol. 71, Page 1352-1358, Year 2015 |
| Publish date | Mar 20, 2015 (structure data deposition date) |
Authors | Pinard, M.A. / Aggarwal, M. / Mahon, B.P. / Tu, C. / McKenna, R. |
External links | Acta Crystallogr F Struct Biol Commun / PubMed:26457530 |
| Methods | X-ray diffraction |
| Resolution | 1.45 - 1.8 Å |
| Structure data | ![]() PDB-4ywp: ![]() PDB-4zao: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
| Source |
|
Keywords | LYASE / alpha-carbonic anhydrase / CA IX mimic / sucrose |
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homo sapiens (human)
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