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-Structure paper
Title | Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 113, Page 2092-2097, Year 2016 |
Publish date | Feb 27, 2015 (structure data deposition date) |
Authors | Hattori, T. / Lai, D. / Dementieva, I.S. / Montano, S.P. / Kurosawa, K. / Zheng, Y. / Akin, L.R. / Swist-Rosowska, K.M. / Grzybowski, A.T. / Koide, A. ...Hattori, T. / Lai, D. / Dementieva, I.S. / Montano, S.P. / Kurosawa, K. / Zheng, Y. / Akin, L.R. / Swist-Rosowska, K.M. / Grzybowski, A.T. / Koide, A. / Krajewski, K. / Strahl, B.D. / Kelleher, N.L. / Ruthenburg, A.J. / Koide, S. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:26862167 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.53 Å |
Structure data | PDB-4yhp: PDB-4yhy: PDB-4yhz: |
Chemicals | ChemComp-HOH: ChemComp-M3L: ChemComp-GOL: ChemComp-SO4: |
Source |
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Keywords | IMMUNE SYSTEM / Antibody / Fab / Head-to-head dimerization / H3K9me3 / Trimethylated Lys / H3K4me3 |