Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
Journal, issue, pages	J. Am. Chem. Soc., Vol. 137, Page 7835-7842, Year 2015
Publish date	Feb 12, 2015 (structure data deposition date)
Authors	Huber, E.M. / de Bruin, G. / Heinemeyer, W. / Paniagua Soriano, G. / Overkleeft, H.S. / Groll, M.
External links	J. Am. Chem. Soc. / PubMed:26020686
Methods	X-ray diffraction
Resolution	2.4 - 2.9 Å
Structure data	PDB-4y69: Yeast 20S proteasome in complex with Ac-PAD-ep Method: X-RAY DIFFRACTION / Resolution: 2.9 Å PDB-4y6a: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAD-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y6v: Yeast 20S proteasome in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y6z: Yeast 20S proteasome in complex with Ac-PAL-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y70: Yeast 20S proteasome in complex with Ac-LAV-ep Method: X-RAY DIFFRACTION / Resolution: 2.4 Å PDB-4y74: Yeast 20S proteasome in complex with Ac-LAL-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y75: Yeast 20S proteasome in complex with Ac-PAF-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y77: Yeast 20S proteasome in complex with Ac-LAF-ep Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-4y78: Yeast 20S proteasome in complex with Ac-LAD-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y7w: Yeast 20S proteasome in complex with Ac-LAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-4y7x: Yeast 20S proteasome in complex with Ac-PAA-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y7y: Yeast 20S proteasome in complex with Ac-LAA-ep Method: X-RAY DIFFRACTION / Resolution: 2.4 Å PDB-4y80: Yeast 20S proteasome in complex with Ac-LAI-ep Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-4y81: Yeast 20S proteasome in complex with Ac-PAY-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y82: Yeast 20S proteasome in complex with Ac-LAY-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y84: Yeast 20S proteasome in complex with N3-A(4,4-F2P)nLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8g: Yeast 20S proteasome in complex with N3-APnLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y8h: Yeast 20S proteasome in complex with N3-APAL-ep Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-4y8i: Yeast 20S proteasome in complex with Ac-PLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y8j: Yeast 20S proteasome in complex with Ac-LLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8k: Yeast 20S proteasome in complex with H-APLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y8l: Yeast 20S proteasome in complex with Ac-APLL-ep Method: X-RAY DIFFRACTION / Resolution: 2.4 Å PDB-4y8m: Yeast 20S proteasome beta7-delta7_Cter mutant Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y8n: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y8o: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAF-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8p: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAL-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y8q: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAY-ep Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4y8r: Yeast 20S proteasome beta2-H116D mutant Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8s: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-LAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8t: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4y8u: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAD-ep Method: X-RAY DIFFRACTION / Resolution: 2.9 Å PDB-4y9y: Yeast 20S proteasome beta2-H116E mutant Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4y9z: Yeast 20S proteasome beta2-H116E mutant in complex with Ac-LAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4ya0: Yeast 20S proteasome beta2-H116E mutant in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-4ya1: Yeast 20S proteasome beta2-H116N mutant Method: X-RAY DIFFRACTION / Resolution: 2.9 Å PDB-4ya2: Yeast 20S proteasome beta2-H116N mutant in complex with Ac-LAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4ya3: Yeast 20S proteasome beta2-H116N mutant in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4ya4: Yeast 20S proteasome beta2-H114D mutant Method: X-RAY DIFFRACTION / Resolution: 2.9 Å PDB-4ya5: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.5 Å PDB-4ya7: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-LAE-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å PDB-4ya9: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-LAD-ep Method: X-RAY DIFFRACTION / Resolution: 2.7 Å
Chemicals	ChemComp-MG: Unknown entry ChemComp-CL: Unknown entry ChemComp-HOH: WATER ChemComp-MES: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH bufferYM ChemComp-K*: Unknown entry
Source	saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast) synthetic construct (others) saccharomyces cerevisiae (brewer's yeast) saccharomyces cerevisiae s288c (yeast) scientific construct (others)
Keywords	HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / Proteasome / Inhibitor / Binding Analysis / Mutant / HYDROLASE