Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
Journal, issue, pages	Acs Med. Chem. Lett., Vol. 6, Page 655-659, Year 2015
Publish date	Feb 9, 2015 (structure data deposition date)
Authors	Mitchell, L.H. / Drew, A.E. / Ribich, S.A. / Rioux, N. / Swinger, K.K. / Jacques, S.L. / Lingaraj, T. / Boriack-Sjodin, P.A. / Waters, N.J. / Wigle, T.J. ...Mitchell, L.H. / Drew, A.E. / Ribich, S.A. / Rioux, N. / Swinger, K.K. / Jacques, S.L. / Lingaraj, T. / Boriack-Sjodin, P.A. / Waters, N.J. / Wigle, T.J. / Moradei, O. / Jin, L. / Riera, T. / Porter-Scott, M. / Moyer, M.P. / Smith, J.J. / Chesworth, R. / Copeland, R.A.
External links	Acs Med. Chem. Lett. / PubMed:26101569
Methods	X-ray diffraction
Resolution	2.1 - 2.37 Å
Structure data	PDB-4y2h: Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor Method: X-RAY DIFFRACTION / Resolution: 2.37 Å PDB-4y30: Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and EPZ020411 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å
Chemicals	ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE ChemComp-49K: N-{[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methyl}-N-methylethane-1,2-diamine ChemComp-GOL: GLYCEROL ChemComp-HOH: WATER ChemComp-49L: N,N'-dimethyl-N-({3-[4-({trans-3-[2-(tetrahydro-2H-pyran-4-yl)ethoxy]cyclobutyl}oxy)phenyl]-1H-pyrazol-4-yl}methyl)ethane-1,2-diamine ChemComp-MG: Unknown entry
Source	homo sapiens (human)
Keywords	TRANSFERASE