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-Structure paper
Title | Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 6, Page 655-659, Year 2015 |
Publish date | Feb 9, 2015 (structure data deposition date) |
![]() | Mitchell, L.H. / Drew, A.E. / Ribich, S.A. / Rioux, N. / Swinger, K.K. / Jacques, S.L. / Lingaraj, T. / Boriack-Sjodin, P.A. / Waters, N.J. / Wigle, T.J. ...Mitchell, L.H. / Drew, A.E. / Ribich, S.A. / Rioux, N. / Swinger, K.K. / Jacques, S.L. / Lingaraj, T. / Boriack-Sjodin, P.A. / Waters, N.J. / Wigle, T.J. / Moradei, O. / Jin, L. / Riera, T. / Porter-Scott, M. / Moyer, M.P. / Smith, J.J. / Chesworth, R. / Copeland, R.A. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.37 Å |
Structure data | ![]() PDB-4y2h: ![]() PDB-4y30: |
Chemicals | ![]() ChemComp-SAH: ![]() ChemComp-49K: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-49L: ![]() ChemComp-MG: |
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![]() | TRANSFERASE |