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TitleFunctionalization of Ruthenium(II)( eta 6 -p-cymene)(3-hydroxy-2-pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies.
Journal, issue, pagesChempluschem, Vol. 82, Page 841-847, Year 2017
Publish dateJan 26, 2015 (structure data deposition date)
AuthorsHanif, M. / Meier, S.M. / Adhireksan, Z. / Henke, H. / Martic, S. / Movassaghi, S. / Labib, M. / Kandioller, W. / Jamieson, S.M.F. / Hejl, M. ...Hanif, M. / Meier, S.M. / Adhireksan, Z. / Henke, H. / Martic, S. / Movassaghi, S. / Labib, M. / Kandioller, W. / Jamieson, S.M.F. / Hejl, M. / Jakupec, M.A. / Kraatz, H.B. / Davey, C.A. / Keppler, B.K. / Hartinger, C.G.
External linksChempluschem / PubMed:31961568
MethodsX-ray diffraction
Resolution3.18 Å
Structure data

PDB-4xuj:
Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound
Method: X-RAY DIFFRACTION / Resolution: 3.18 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-4A6:
[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)benzene]ruthenium

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • xenopus laevis (African clawed frog)
  • synthetic construct (others)
KeywordsDNA-BINDING PROTEIN/DNA / nucleosome / ruthenium agent / DNA-BINDIG PROTEIN-DNA complex / DNA-BINDING PROTEIN-DNA complex

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