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Structure paper

TitleStructural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Journal, issue, pagesNucleic Acids Res., Vol. 43, Page 5236-5248, Year 2015
Publish dateJan 19, 2015 (structure data deposition date)
AuthorsIbsen, M.S. / Gad, H.H. / Andersen, L.L. / Hornung, V. / Julkunen, I. / Sarkar, S.N. / Hartmann, R.
External linksNucleic Acids Res. / PubMed:25925578
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-4xq7:
The crystal structure of the OAS-like domain (OLD) of human OASL
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / OAS / oligoadenylate synthetase / oligoadenylate synthetase-like / OASL / 2'-5' oligoadenylate synthetase

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