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TitleX-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor.
Journal, issue, pagesOrg. Biomol. Chem., Vol. 13, Page 4064-4069, Year 2015
Publish dateDec 21, 2014 (structure data deposition date)
AuthorsAlterio, V. / Tanc, M. / Ivanova, J. / Zalubovskis, R. / Vozny, I. / Monti, S.M. / Di Fiore, A. / De Simone, G. / Supuran, C.T.
External linksOrg. Biomol. Chem. / PubMed:25733161
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-4xe1:
Human carbonic anhydrase II in complex with 6-SULFAMOYL-SACCHARIN
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HGB:
4-(HYDROXYMERCURY)BENZOIC ACID

ChemComp-IL5:
3-oxo-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / Cytoplasm / Inhibitor

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