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TitleCytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Journal, issue, pagesNat Commun, Vol. 6, Page 6011-6011, Year 2015
Publish dateNov 4, 2014 (structure data deposition date)
AuthorsTrowitzsch, S. / Viola, C. / Scheer, E. / Conic, S. / Chavant, V. / Fournier, M. / Papai, G. / Ebong, I.O. / Schaffitzel, C. / Zou, J. ...Trowitzsch, S. / Viola, C. / Scheer, E. / Conic, S. / Chavant, V. / Fournier, M. / Papai, G. / Ebong, I.O. / Schaffitzel, C. / Zou, J. / Haffke, M. / Rappsilber, J. / Robinson, C.V. / Schultz, P. / Tora, L. / Berger, I.
External linksNat Commun / PubMed:25586196
MethodsX-ray diffraction
Resolution1.75 - 1.909 Å
Structure data

PDB-4wv4:
Heterodimer of TAF8/TAF10
Method: X-RAY DIFFRACTION / Resolution: 1.909 Å

PDB-4wv6:
Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / TBP-associated factor / Heterodimer / Histone fold domain / TRANSPORT PROTEIN / Nuclear import / Armadillo repeats / NLS

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