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-Structure paper
| Title | Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1). |
|---|---|
| Journal, issue, pages | Acs Med. Chem. Lett., Vol. 5, Page 1308-1312, Year 2014 |
| Publish date | Sep 18, 2014 (structure data deposition date) |
Authors | Fang, C. / D'Souza, B. / Thompson, C.F. / Clifton, M.C. / Fairman, J.W. / Fulroth, B. / Leed, A. / McCarren, P. / Wang, L. / Wang, Y. ...Fang, C. / D'Souza, B. / Thompson, C.F. / Clifton, M.C. / Fairman, J.W. / Fulroth, B. / Leed, A. / McCarren, P. / Wang, L. / Wang, Y. / Feau, C. / Kaushik, V.K. / Palmer, M. / Wei, G. / Golub, T.R. / Hubbard, B.K. / Serrano-Wu, M.H. |
External links | Acs Med. Chem. Lett. / PubMed:25516789 |
| Methods | X-ray diffraction |
| Resolution | 1.85 Å |
| Structure data | ![]() PDB-4wgi: |
| Chemicals | ![]() ChemComp-3M6: ![]() ChemComp-MG: ![]() ChemComp-FMT: ![]() ChemComp-HOH: |
| Source |
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Keywords | apoptosis/inhibitor / Fusion protein / MBP / transport protein / transport protein-inhibitor complex / apoptosis-inhibitor complex |
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homo sapiens (human)
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