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Structure paper

TitleThe antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
Journal, issue, pagesJ. Mol. Biol., Vol. 416, Page 571-578, Year 2012
Publish dateDec 5, 2011 (structure data deposition date)
AuthorsBulkley, D. / Johnson, F. / Steitz, T.A.
External linksJ. Mol. Biol. / PubMed:22240456
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-4v8a:
The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-T8B:
Thermorubin

ChemComp-MG:
Unknown entry

Source
  • thermus thermophilus (bacteria)
KeywordsRIBOSOME/antibiotic / Ribosome / Protein synthesis / Thermorubin / RIBOSOME-antibiotic complex

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