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Structure paper

TitleInsights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 16, Page 528-533, Year 2009
Publish dateMar 24, 2009 (structure data deposition date)
AuthorsVoorhees, R.M. / Weixlbaumer, A. / Loakes, D. / Kelley, A.C. / Ramakrishnan, V.
External linksNat. Struct. Mol. Biol. / PubMed:19363482
MethodsX-ray diffraction
Resolution3.3 - 3.5 Å
Structure data

PDB-4v5c:
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA.
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-4v5d:
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

ChemComp-ZN:
Unknown entry

Source
  • escherichia coli k-12 (bacteria)
  • thermus thermophilus (bacteria)
  • synthetic construct (others)
  • escherichia coli (E. coli)
KeywordsRIBOSOME / METAL-BINDING / RIBOSOMAL PROTEIN / RIBONUCLEOPROTEIN / TRANSLATION / TRNA-BINDING / RRNA-BINDING / TRNA / MRNA / RNA-BINDING / ZINC-FINGER

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