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| Title | Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells |
|---|---|
| Journal, issue, pages | Chemmedchem, Vol. 6, Page 665-670, Year 2015 |
| Publish date | Aug 27, 2014 (structure data deposition date) |
Authors | Rodriguez, V. / Valente, S. / Rovida, S. / Rotili, D. / Stazi, G. / Lucidi, A. / Ciossani, G. / Mattevi, A. / Botrugno, O.A. / Dessanti, P. ...Rodriguez, V. / Valente, S. / Rovida, S. / Rotili, D. / Stazi, G. / Lucidi, A. / Ciossani, G. / Mattevi, A. / Botrugno, O.A. / Dessanti, P. / Mercurio, C. / Vianello, P. / Minucci, S. / Varasi, M. / Mai, A. |
External links | Chemmedchem / Search PubMed |
| Methods | X-ray diffraction |
| Resolution | 2.85 Å |
| Structure data | ![]() PDB-4uxn: |
| Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-M8A: |
| Source |
|
Keywords | OXIDOREDUCTASE / COVALENT INHIBITOR / TRANYLCYPROMINE |
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