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TitleQuinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT.
Journal, issue, pagesBiochemistry, Vol. 54, Page 47-59, Year 2015
Publish dateJul 30, 2014 (structure data deposition date)
AuthorsLeung, K.K. / Shilton, B.H.
External linksBiochemistry / PubMed:25379648
MethodsX-ray diffraction
Resolution1.48 - 1.96 Å
Structure data

PDB-4u7f:
Reduced quinone reductase 2 in complex with CK2 inhibitor DMAT
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4u7g:
Oxidized quinone reductase 2 in complex with CK2 inhibitor TBBz
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-4u7h:
Oxidized quinone reductase 2 in complex with CK2 inhibitor DMAT
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-K25:
4,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZIMIDAZOL-2-AMINE

ChemComp-HOH:
WATER

ChemComp-K17:
4,5,6,7-TETRABROMO-BENZIMIDAZOLE

Source
  • homo sapiens (human)
KeywordsOxidoreductase/Inhibitor / reduced quinone reductase 2 / DMAT / CK2 inhibitor / Oxidoreductase-Inhibitor complex / quinone reductase 2

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