Movie
Controller
Structure viewers
About Yorodumi Papers
+Search query
-Structure paper
| Title | Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 57, Page 8503-8516, Year 2014 |
| Publish date | Jun 6, 2014 (structure data deposition date) |
 Authors | Fu, J. / Tjandra, M. / Becker, C. / Bednarczyk, D. / Capparelli, M. / Elling, R. / Hanna, I. / Fujimoto, R. / Furegati, M. / Karur, S. ...Fu, J. / Tjandra, M. / Becker, C. / Bednarczyk, D. / Capparelli, M. / Elling, R. / Hanna, I. / Fujimoto, R. / Furegati, M. / Karur, S. / Kasprzyk, T. / Knapp, M. / Leung, K. / Li, X. / Lu, P. / Mergo, W. / Miault, C. / Ng, S. / Parker, D. / Peng, Y. / Roggo, S. / Rivkin, A. / Simmons, R.L. / Wang, M. / Wiedmann, B. / Weiss, A.H. / Xiao, L. / Xie, L. / Xu, W. / Yifru, A. / Yang, S. / Zhou, B. / Sweeney, Z.K. |
 External links | J. Med. Chem. / PubMed:25310383 |
| Methods | X-ray diffraction |
| Resolution | 2.39 Å |
| Structure data |  PDB-4tot: |
| Chemicals |  ChemComp-P6G:  ChemComp-SO4:  ChemComp-HOH: |
| Source |
|
 Keywords | ISOMERASE/ISOMERASE Inhibitor / Inhibitor / Complex / Cyclosporin / ISOMERASE-ISOMERASE Inhibitor complex |
rattus norvegicus (Norway rat)