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TitleBiochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target.
Journal, issue, pagesPlos One, Vol. 9, Page e113568-e113568, Year 2014
Publish dateOct 21, 2014 (structure data deposition date)
AuthorsGurcha, S.S. / Usha, V. / Cox, J.A. / Futterer, K. / Abrahams, K.A. / Bhatt, A. / Alderwick, L.J. / Reynolds, R.C. / Loman, N.J. / Nataraj, V. ...Gurcha, S.S. / Usha, V. / Cox, J.A. / Futterer, K. / Abrahams, K.A. / Bhatt, A. / Alderwick, L.J. / Reynolds, R.C. / Loman, N.J. / Nataraj, V. / Alemparte, C. / Barros, D. / Lloyd, A.J. / Ballell, L. / Hobrath, J.V. / Besra, G.S.
External linksPlos One / PubMed:25409504
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4rmf:
Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-3SY:
2,2-bis(hydroxymethyl)propane-1,3-diol

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

Source
  • mycobacterium smegmatis (bacteria)
KeywordsLIGASE / alpha and beta proteins / tRNA synthetase / tRNA

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