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Title | Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 6, Page 782-786, Year 2015 |
Publish date | Sep 18, 2014 (structure data deposition date) |
![]() | He, R. / Yu, Z.H. / Zhang, R.Y. / Wu, L. / Gunawan, A.M. / Lane, B.S. / Shim, J.S. / Zeng, L.F. / He, Y. / Chen, L. ...He, R. / Yu, Z.H. / Zhang, R.Y. / Wu, L. / Gunawan, A.M. / Lane, B.S. / Shim, J.S. / Zeng, L.F. / He, Y. / Chen, L. / Wells, C.D. / Liu, J.O. / Zhang, Z.Y. |
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Methods | X-ray diffraction |
Resolution | 1.601 Å |
Structure data | ![]() PDB-4rdd: |
Chemicals | ![]() ChemComp-3LU: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex |