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Structure paper

TitleThe role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 137, Page 2748-2756, Year 2015
Publish dateSep 17, 2014 (structure data deposition date)
AuthorsKholodar, S.A. / Allen, C.L. / Gulick, A.M. / Murkin, A.S.
External linksJ. Am. Chem. Soc. / PubMed:25642788
MethodsX-ray diffraction
Resolution2.294 Å
Structure data

PDB-4rcv:
M. tuberculosis 1-deoxy-d-xylulose-5-phosphate reductoisomerase bound to 1-deoxy-L-erythrulose
Method: X-RAY DIFFRACTION / Resolution: 2.294 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-DE2:
1-deoxy-L-erythrulose

ChemComp-PO3:
PHOSPHITE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsOXIDOREDUCTASE / Reductoisomerase

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