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-Structure paper
Title | Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 24, Page 5704-5709, Year 2014 |
Publish date | Jul 24, 2014 (structure data deposition date) |
![]() | Gazzard, L. / Appleton, B. / Chapman, K. / Chen, H. / Clark, K. / Drobnick, J. / Goodacre, S. / Halladay, J. / Lyssikatos, J. / Schmidt, S. ...Gazzard, L. / Appleton, B. / Chapman, K. / Chen, H. / Clark, K. / Drobnick, J. / Goodacre, S. / Halladay, J. / Lyssikatos, J. / Schmidt, S. / Sideris, S. / Wiesmann, C. / Williams, K. / Wu, P. / Yen, I. / Malek, S. |
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Methods | X-ray diffraction |
Resolution | 1.75 - 2.15 Å |
Structure data | ![]() PDB-4qye: ![]() PDB-4qyf: ![]() PDB-4qyg: ![]() PDB-4qyh: |
Chemicals | ![]() ChemComp-3DL: ![]() ChemComp-HOH: ![]() ChemComp-3DV: ![]() ChemComp-3DW: ![]() ChemComp-3DX: |
Source |
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![]() | Transferase/Transferase Inhibitor / protein kinase / phosphotransfer catalyst / Transferase-Transferase Inhibitor complex |