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-Structure paper
Title | Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3). |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 1204-1217, Year 2018 |
Publish date | Jun 27, 2014 (structure data deposition date) |
Authors | Kaniskan, H.U. / Eram, M.S. / Zhao, K. / Szewczyk, M.M. / Yang, X. / Schmidt, K. / Luo, X. / Xiao, S. / Dai, M. / He, F. ...Kaniskan, H.U. / Eram, M.S. / Zhao, K. / Szewczyk, M.M. / Yang, X. / Schmidt, K. / Luo, X. / Xiao, S. / Dai, M. / He, F. / Zang, I. / Lin, Y. / Li, F. / Dobrovetsky, E. / Smil, D. / Min, S.J. / Lin-Jones, J. / Schapira, M. / Atadja, P. / Li, E. / Barsyte-Lovejoy, D. / Arrowsmith, C.H. / Brown, P.J. / Liu, F. / Yu, Z. / Vedadi, M. / Jin, J. |
External links | J. Med. Chem. / PubMed:29244490 |
Methods | X-ray diffraction |
Resolution | 2.08 Å |
Structure data | PDB-4qqn: |
Chemicals | ChemComp-3BQ: ChemComp-GOL: ChemComp-CL: ChemComp-UNX: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / PRMT3 / Structural Genomics / Structural Genomics Consortium / SGC / Epigenetics |