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TitleCrystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345
Journal, issue, pagesTo be Published
Publish dateJun 27, 2014 (structure data deposition date)
AuthorsDombrovski, L. / Dong, A. / Wernimont, A. / Smil, D. / Getlik, M. / Senisterra, G. / Poda, G. / Al-Awar, R. / Bountra, C. / Arrowsmith, C.H. ...Dombrovski, L. / Dong, A. / Wernimont, A. / Smil, D. / Getlik, M. / Senisterra, G. / Poda, G. / Al-Awar, R. / Bountra, C. / Arrowsmith, C.H. / Edwards, A.M. / Brown, P.J. / Schapira, M. / Vedadi, M. / Wu, H.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-4qqe:
Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-37F:
N-[2-(4-methylpiperazin-1-yl)-5-(quinolin-3-yl)phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / WDR5 / Structural Genomics / Structural Genomics Consortium / SGC

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