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TitleInteractions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II).
Journal, issue, pagesInorg. Chem., Vol. 53, Page 7806-7808, Year 2014
Publish dateMay 26, 2014 (structure data deposition date)
AuthorsMessori, L. / Marzo, T. / Michelucci, E. / Russo Krauss, I. / Navarro-Ranninger, C. / Quiroga, A.G. / Merlino, A.
External linksInorg. Chem. / PubMed:25025479
MethodsX-ray diffraction
Resolution2 - 2.51 Å
Structure data

PDB-4qgz:
X-ray structure of the adduct formed between hen egg white lysozyme and trans-dimethylamine methylamine dichlorido platinum(II)
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-4qh3:
X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-I83:
bis(chloranyl)-(dimethylamino)-(methylamino)platinum

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / Lysozyme fold / O-GLYCOSYL HYDROLASE / RNA BINDING

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