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TitleThermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development.
Journal, issue, pagesBiochemistry, Vol. 53, Page 3790-3795, Year 2014
Publish dateApr 10, 2014 (structure data deposition date)
AuthorsMartinez, M. / Ahmed, A.H. / Loh, A.P. / Oswald, R.E.
External linksBiochemistry / PubMed:24850223
MethodsX-ray diffraction
Resolution2.03 Å
Structure data

PDB-4q30:
Nitrowillardiine bound to the ligand binding domain of GluA2 at pH 3.5
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-NWD:
3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSPORT PROTEIN / glutamate receptor / GluA2 / GluR2 / AMPA receptor / LBD / neurotransmitter receptor / nitrowillardiine

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