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Structure paper

TitleUnravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases.
Journal, issue, pagesNat Commun, Vol. 5, Page 5141-5141, Year 2014
Publish dateApr 7, 2014 (structure data deposition date)
AuthorsMoutiez, M. / Schmitt, E. / Seguin, J. / Thai, R. / Favry, E. / Belin, P. / Mechulam, Y. / Gondry, M.
External linksNat Commun / PubMed:25284085
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-4q24:
Crystal structure of Cyclo(L-leucyl-L-phenylalanyl) synthase
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-XVE:
PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE

ChemComp-HOH:
WATER

Source
  • streptomyces noursei (bacteria)
Keywordstransferase/transferase inhibitor / Rossmann fold / cyclodipeptide synthase / aminoacyl-tRNA / transferase-transferase inhibitor complex

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