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TitleA peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 96, Page 6102-6106, Year 1999
Publish dateMay 7, 1999 (structure data deposition date)
AuthorsOberfield, J.L. / Collins, J.L. / Holmes, C.P. / Goreham, D.M. / Cooper, J.P. / Cobb, J.E. / Lenhard, J.M. / Hull-Ryde, E.A. / Mohr, C.P. / Blanchard, S.G. ...Oberfield, J.L. / Collins, J.L. / Holmes, C.P. / Goreham, D.M. / Cooper, J.P. / Cobb, J.E. / Lenhard, J.M. / Hull-Ryde, E.A. / Mohr, C.P. / Blanchard, S.G. / Parks, D.J. / Moore, L.B. / Lehmann, J.M. / Plunket, K. / Miller, A.B. / Milburn, M.V. / Kliewer, S.A. / Willson, T.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:10339548
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-4prg:
0072 PARTIAL AGONIST PPAR GAMMA COCRYSTAL
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-072:
(+/-)(2S,5S)-3-(4-(4-CARBOXYPHENYL)BUTYL)-2-HEPTYL-4-OXO-5-THIAZOLIDINE

Source
  • homo sapiens (human)
KeywordsRECEPTOR / THIAZOLIDINONE / LIGAND-BINDING DOMAIN / NUCLEAR RECEPTOR / ORPHAN RECEPTOR

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