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Structure paper

TitleBromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome.
Journal, issue, pagesPlos Biol., Vol. 13, Page e1002316-e1002316, Year 2015
Publish dateMay 15, 2014 (structure data deposition date)
AuthorsSchulz, D. / Mugnier, M.R. / Paulsen, E.M. / Kim, H.S. / Chung, C.W. / Tough, D.F. / Rioja, I. / Prinjha, R.K. / Papavasiliou, F.N. / Debler, E.W.
External linksPlos Biol. / PubMed:26646171
MethodsX-ray diffraction
Resolution1.251 Å
Structure data

PDB-4pkl:
Bromodomain of Trypanosoma brucei BDF2 With IBET-151
Method: X-RAY DIFFRACTION / Resolution: 1.251 Å

Chemicals

ChemComp-1GH:
7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-K:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei brucei (eukaryote)
KeywordsSIGNALING PROTEIN/INHIBITOR / SIGNALING PROTEIN / INHIBITOR / HISTONE / EPIGENETIC READER / SIGNALING PROTEIN-INHIBITOR complex

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