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-Structure paper
Title | High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. |
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Journal, issue, pages | Nature, Vol. 513, Page 124-127, Year 2014 |
Publish date | May 7, 2014 (structure data deposition date) |
Authors | Srivastava, A. / Yano, J. / Hirozane, Y. / Kefala, G. / Gruswitz, F. / Snell, G. / Lane, W. / Ivetac, A. / Aertgeerts, K. / Nguyen, J. ...Srivastava, A. / Yano, J. / Hirozane, Y. / Kefala, G. / Gruswitz, F. / Snell, G. / Lane, W. / Ivetac, A. / Aertgeerts, K. / Nguyen, J. / Jennings, A. / Okada, K. |
External links | Nature / PubMed:25043059 |
Methods | X-ray diffraction |
Resolution | 2.332 Å |
Structure data | PDB-4phu: |
Chemicals | ChemComp-2YB: ChemComp-OLC: ChemComp-1PE: ChemComp-DMS: ChemComp-HOH: |
Source |
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Keywords | Fatty acid binding protein/Hydrolase / GPR40 / fatty acid binding protein / class A / g-protein coupled receptor / type II diabetes / TAK-875 / fasiglifam / Fatty acid binding protein-Hydrolase complex |