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TitleSynthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins?
Journal, issue, pagesChemistry, Vol. 21, Page 1978-1991, Year 2015
Publish dateApr 28, 2014 (structure data deposition date)
AuthorsFrancois-Heude, M. / Mendez-Ardoy, A. / Cendret, V. / Lafite, P. / Daniellou, R. / Ortiz Mellet, C. / Garcia Fernandez, J.M. / Moreau, V. / Djedaini-Pilard, F.
External linksChemistry / PubMed:25483029
MethodsX-ray diffraction
Resolution2.04 Å
Structure data

PDB-4pf5:
Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-M3N:
4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • canavalia ensiformis (jack bean)
KeywordsSUGAR BINDING PROTEIN / Lectin / High mannose

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