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TitleLsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 14235-14240, Year 2014
Publish dateMar 4, 2014 (structure data deposition date)
AuthorsMarques, J.C. / Oh, I.K. / Ly, D.C. / Lamosa, P. / Ventura, M.R. / Miller, S.T. / Xavier, K.B.
External linksProc. Natl. Acad. Sci. USA / PubMed:25225400
MethodsX-ray diffraction
Resolution2.51 Å
Structure data

PDB-4p2v:
Structure of the AI-2 processing enzyme LsrF in complex with the product of the LsrG reaction P-HPD
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-26T:
(3R)-3-hydroxy-2,4-dioxopentyl dihydrogen phosphate

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsLYASE / Thiolase

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