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-Structure paper
Title | X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 2393-2412, Year 2014 |
Publish date | Jan 28, 2014 (structure data deposition date) |
![]() | Baez-Santos, Y.M. / Barraza, S.J. / Wilson, M.W. / Agius, M.P. / Mielech, A.M. / Davis, N.M. / Baker, S.C. / Larsen, S.D. / Mesecar, A.D. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.5 Å |
Structure data | ![]() PDB-4ovz: ![]() PDB-4ow0: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-P85: ![]() ChemComp-DMS: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-S88: ![]() ChemComp-GOL: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / CoV / coronavirus / HCoV / human coronavirus / SARS / severe acute respiratory syndrome / MERS / Middle East respiratory syndrome / PLpro / protease inhibitor / complex / DUB / deubiquitinating enzyme / HYDROLASE-HYDROLASE INHIBITOR complex / papain-like protease; inhibitor |