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Structure paper

TitleProduction of a novel N-monomethylated dideoxysugar.
Journal, issue, pagesBiochemistry, Vol. 53, Page 1105-1107, Year 2014
Publish dateFeb 8, 2014 (structure data deposition date)
AuthorsThoden, J.B. / Holden, H.M.
External linksBiochemistry / PubMed:24512254
MethodsX-ray diffraction
Resolution1.6 - 2.2 Å
Structure data

PDB-4oqd:
Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Qui3NMe2
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4oqe:
Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Fuc3NMe
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-QDM:
TDP-3,6-dideoxy-3-N,N-dimethylglucose

ChemComp-HOH:
WATER

ChemComp-MMF:
dTDP-3-N-methylamino-3,6-dideoxygalactose

Source
  • streptomyces fradiae (bacteria)
KeywordsTRANSFERASE / SAM methyltransferase / N-methyltransferase / S-adenosylmethionine

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