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Structure paper

TitleMolecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page E4648-E4657, Year 2014
Publish dateJan 28, 2014 (structure data deposition date)
AuthorsRoy, S. / Ly, D. / Li, N.S. / Altman, J.D. / Piccirilli, J.A. / Moody, D.B. / Adams, E.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:25298532
MethodsX-ray diffraction
Resolution2.705 - 3.008 Å
Structure data

PDB-4onh:
Crystal Structure of DN6 TCR
Method: X-RAY DIFFRACTION / Resolution: 3.008 Å

PDB-4ono:
CD1c in complex with PM (phosphomycoketide)
Method: X-RAY DIFFRACTION / Resolution: 2.705 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PMK:
(4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate

ChemComp-MLI:
MALONATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Ig fold / TCR / Antigen recognition / MHC like / CD1c / Antigen presentation

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