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Structure paper

TitleStructural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 10502-10509, Year 2014
Publish dateJan 23, 2014 (structure data deposition date)
AuthorsGalkin, A. / Kulakova, L. / Lim, K. / Chen, C.Z. / Zheng, W. / Turko, I.V. / Herzberg, O.
External linksJ. Biol. Chem. / PubMed:24558036
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-4olc:
Carbamate kinase from Giardia lamblia thiocarbamoylated by disulfiram on Cys242
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-DCD:
DIETHYLCARBAMODITHIOIC ACID

ChemComp-HOH:
WATER

Source
  • giardia lamblia (eukaryote)
KeywordsTRANSFERASE / ADP / Mg2+ / carbamate / carbamoyl phosphate

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