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Structure paper

TitleRAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Journal, issue, pagesJ. Exp. Med., Vol. 210, Page 2447-2463, Year 2013
Publish dateJan 19, 2014 (structure data deposition date)
AuthorsSirois, C.M. / Jin, T. / Miller, A.L. / Bertheloot, D. / Nakamura, H. / Horvath, G.L. / Mian, A. / Jiang, J. / Schrum, J. / Bossaller, L. ...Sirois, C.M. / Jin, T. / Miller, A.L. / Bertheloot, D. / Nakamura, H. / Horvath, G.L. / Mian, A. / Jiang, J. / Schrum, J. / Bossaller, L. / Pelka, K. / Garbi, N. / Brewah, Y. / Tian, J. / Chang, C. / Chowdhury, P.S. / Sims, G.P. / Kolbeck, R. / Coyle, A.J. / Humbles, A.A. / Xiao, T.S. / Latz, E.
External linksJ. Exp. Med. / PubMed:24081950
MethodsX-ray diffraction
Resolution3.101 - 3.104 Å
Structure data

PDB-4oi7:
RAGE recognizes nucleic acids and promotes inflammatory responses to DNA
Method: X-RAY DIFFRACTION / Resolution: 3.104 Å

PDB-4oi8:
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Method: X-RAY DIFFRACTION / Resolution: 3.101 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / SIGNALING PROTEIN/DNA / protein-DNA complex / Ig fold / DNA binding / extracellular receptor / SIGNALING PROTEIN-DNA complex

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